Group Comparisons Involving Zero-Inflated Count Data in Clinical Trials
نویسندگان
چکیده
منابع مشابه
Semiparametric analysis of zero-inflated count data.
Medical and public health research often involve the analysis of count data that exhibit a substantially large proportion of zeros, such as the number of heart attacks and the number of days of missed primary activities in a given period. A zero-inflated Poisson regression model, which hypothesizes a two-point heterogeneity in the population characterized by a binary random effect, is generally...
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Ecological phenomena are often measured in the form of count data. These data can be analyzed using generalized linear mixed models (GLMMs) when observations are correlated in ways that require random effects. However, count data are often zero-inflated, containing more zeros than would be expected from the standard error distributions used in GLMMs, e.g., parasite counts may be exactly zero fo...
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Different conventional and causal approaches have been proposed for mediation analysis to better understand the mechanism of a treatment. Count and zero-inflated count data occur in biomedicine, economics, and social sciences. This paper considers mediation analysis for count and zero-inflated count data under the potential outcome framework with nonlinear models. When there are post-treatment ...
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We consolidate the zero-inflated Poisson model for count data with excess zeros (Lambert, 1992) and the two-component model approach for serial correlation among repeated observations (Dobbie and Welsh, 2001) for spatial count data. This concurrently addresses the problem of overdispersion and distinguishes zeros that arise due to random sampling from those that arise due to inherent characteri...
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Background: The instrumental activities of daily living (IADLs) are important index of physical functioning in older adult studies. These count outcomes with a large proportion of zeros are often collected in longitudinal studies. Data were from the Hispanic Established Population for Epidemiological Study of the Elderly (HEPESE), a four wave (seven years) longitudinal study of community-dwelli...
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ژورنال
عنوان ژورنال: Japanese Journal of Biometrics
سال: 2014
ISSN: 0918-4430,2185-6494
DOI: 10.5691/jjb.34.53